Enzolytics, Inc. and the Bulgarian Academy of Sciences Initiate a Cooperative Program Primarily Focusing on Applied and Strategic Research in Immunology for Cancer and HIV/AIDS Applications

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ALLEN, TX / ACCESSWIRE / July 31, 2024 / Enzolytics, Inc. (OTC PINK:ENZC) ("enzolytics.com") (the "Company") announced today that the Company and the Department of Immunology, Bulgarian Academy of Science The Stephan Angeloff Institute of Microbiology have initiated a cooperative effort to expand the use of each other's technology.

The main area of research by the Department of Immunology, through its seven state of the art laboratory facilities, is concentrated on: autoimmunity and autoimmune diseases, allergy, vaccines, cancer and immunomodulators. The effort focuses on the development of new approaches to specific suppression of pathological immune cells through genetic engineering and protein molecules.

The research infrastructure capabilities include:

  • Cell culture rooms with HEPA clean air filter system and laminar flow cabinets, CO2 incubators;

  • Barrier-type SPF animal facility with temperature control and HEPA system for breeding of laboratory mice;

  • Bank of cell hybridomas and lines.

  • BD?LSR II FACS with FCS Express? Diva software allowing analysis of 18-different cell parameters;

  • SACURA? microtome, Leica Cryostat CM1950, Leica TP1020 Automatic Tissue Processor, and Leica Embedding Arcadia equipment for histology and immunohistochemistry;

  • Nikon? light and Leica? DM2000, Leica? DMi8 invert and light microscopes with digital cameras for picture capturing;

  • Leica DM6 B fully automated upright fluorescent microscope;

  • High performance Microplate Reader with advanced LVF MonochromatorsTM for Fluorescence and Luminescence

  • Confocal laser scanning microscopy (CLSM) Nikon Eclipse Ti-U CLSM

  • ELISpot ImmunoSpot? Series 6 Ultimate UV fluorescent Image Analyzer;

  • Bio-Tek? ELISA plate reader with Gen 5.0? software;

  • PCR - C1000 Touch? Thermal Cycler with Dual 48/48 Fast Reaction Module

  • Eppendorf? micro UV/VIS spectrophotometer;

  • Eppendorf BioSpectrometer;

  • Arrayit InnoScan 1100 Microarray Scanner;

  • MACS? cell sorting equipment and products;

  • BioRad? and SciePlas? systems for electrophoresis and immunoblot;

  • Countess? II FL Automated Cell Counter;

  • BioRad? ChemiDoc? MP Imaging System;

  • Basic laboratory instruments and BioRad? NGC Quest? 10 Plus Chromatography System;

The high scale antibody production currently being produced includes:

  • 2c11/DaA3 hamster anti mouse CD3 IgG1

  • 9E10/ C1N mouse anti human C-myc protein

  • 2.4G2/ DABE4 rat anti mouse CD32/16 IgG2b

  • 7G6/Z3C antimouse CR1/2 CD21/CD35

  • PK136/IR5 antimouse NK Ag

  • M5/114/AmA77 rat anti mouse MHC II A-E IgG2b

  • 7D4/JAA12 rat antimouse CD25 IgM

  • GK1.5/PJP6 rat anti mouse CD4 IgG 2b

  • 1D3/ PeCa 1 rat anti mouse CD19 IgG2a

  • 3D9/UJ11 mouse antihuman CR1 IgG1

  • IP2-11-1 influenza virus A/PR/8/34 hemagglutinin intersubunit peptide HA317-341

  • 10F10/ HpS22 mouse antidsDNA IgG2a

  • 53.6/SSa1 rat anti mouse CD8 IgG2a

  • 11B11 rat anti mouse IL4 IgG1

  • S4B6/67DE1 rat anti mouse IL2 IgG2a

  • GL1/MHD2 rat anti mouse CD86 IgG2a

  • I/9 TBE 15 rat IgG2b

  • Z34 anti mouse IgG2a and IgG2b

  • Custom antibody production from client hybridoma